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| Player (age) | From club | To club | Date | Fee | |||
|---|---|---|---|---|---|---|---|
| Show/hide all additional info | Fees in euro (EUR) | ||||||
| 1 |  |  C. Benítez (25) |  Santos Laguna |  CF América | 2011, Jul | 8 000 000 | |
| 2 |  |  N. Araujo (26) | Santos Laguna |  Celta Vigo | 2018, Jul | 7 000 000 | |
| 3 | | O. Alanís (26) | Santos Laguna | 2015, Jul | 4 400 000 | ||
| 4 | | V. Matías Vuoso (24) | Santos Laguna | CF América | 2006, Jul | 4 000 000 | |
| 5 | |  S. Peralta (25) | Santos Laguna |  Tigres UANL | 2004, Jul | 1 800 000 | |
| 6 | | C. Benítez (23) | Santos Laguna |  Birmingham | 2009, Jul | 900 000 | |
| 7 | | S. Muñóz (19) | Santos Laguna |  Newcastle | 2021, Aug | ||
| 8 | |  M. Moreno (22) | Santos Laguna |  Man City | 2019, Jul | ||
| 9 | | A. Marchesín (28) | Santos Laguna | CF América | 2017, Jan | ||
| 10 | |  M. Crosas (26) | Santos Laguna | 2014, Jul | |||