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| Player (age) | From club | To club | Date | Fee | |||
|---|---|---|---|---|---|---|---|
| Show/hide all additional info | Fees in euro (EUR) | ||||||
| 1 |  |  A. Marchesín (26) |  Club Atlético Lanús |  Santos Laguna | 2015, Jan | 4 150 000 | |
| 2 | |  V. Matías Vuoso (25) |  CF América | Santos Laguna | 2007, Jan | 2 650 000 | |
| 3 | | S. Peralta (24) |  Racing Club de Avellaneda | Santos Laguna | 2003, Jul | 2 500 000 | |
| 4 | |  Dória (23) |  Marseille | Santos Laguna | 2018, Jul | 2 000 000 | |
| 5 | | V. Matías Vuoso (21) |  Man City | Santos Laguna | 2003, Jul | 1 500 000 | |
| 6 | |  R. Rodríguez (26) |  Siena | Santos Laguna | 2014, Jan | 1 000 000 | |
| 7 | | S. Muñóz (18) | Santos Laguna | 2021, Jan | |||
| 8 | |  M. Moreno (22) | Man City | Santos Laguna | 2019, Jan | ||
| 9 | | U. Dávila (24) |  Chelsea | Santos Laguna | 2016, Jan | ||
| 10 | |  B. Rabello (21) |  Sevilla | Santos Laguna | 2015, Jul | ||